Best Hangover Pills 2019 – Ranked and Reviewed
By James Petra
Updated on October 02, 2019

With all of the different hangover pills and tablets on the market today, finding the most effective, fast-acting and affordable supplement to support your rough mornings is not easy.

UPDATE: We’ve updated this guide with the latest information and supplements for 2019. We currently rate AfterDrink as the best hangover pill on the market at the moment. We’ll be reviewing and updating this guide with the latest information throughout 2019.

Head to your nearest pharmacy, drugstore, or just hop on Amazon and you’ll see so many different options.

There’s so much choice that it’s actually pretty difficult to pick out the best hangover product for you.

So, how do you figure out which hangover pills actually work and make sure you don’t waste your money on ineffective hype products?

If you’re looking to find the best supplement on the market right now, then you’ve landed on the right page.

In this article, we’re going to focus specifically on hangover pills which are designed to supply your liver with the raw materials it requires to optimally metabolize alcohol.

We’ve paid particular attention to the ingredient formulas, the dosages, and the customer reviews, and have compiled our list of the best five supplements on the market right now.

Here’s a quick peek of our top pick if you don’t want to read the full guide.

Rating Summary Website
AfterDrink AfterDrink ★★★★★ • New Product • Proven Ingredients • Good Reviews Buy Now
Flyby Flyby ★★★★☆ • Uses L-Theanine • Liver Support • Good Reviews Buy Now
Detoxx Detoxx ★★★☆☆ • Uses Milk Thistle • Solid Ingredients • Lower Price Buy Now
Cheers Cheers ★★★☆☆ • Uses Ginger • Strong Brand • Good Reviews Buy Now
Drinkwel Drinkwel ★★☆☆☆ • Many Ingredients • Uses Milk Thistle • Strong Brand Buy Now

What causes hangovers in the first place?

Before we get into our pick of the best hangover pills and how they work, it’s worth taking a look at exactly why hangovers occur in the first place.

So, let’s cover the main reasons why you wake up feeling rough after a night of drinking…

1) Dehydration

Alcohol is a diuretic which means it makes your kidneys produce more urine. This results in more urine being produced than the amount of fluid you’re consuming. The net effect of this is a loss of water and therefore dehydration.

It’s estimated that 1 unit of alcohol (equivalent to one shot of a strong spirit like vodka) makes you produce approximately 100ml of urine. When you add the units up over a night out drinking, you can understand why you need so many toilet stops.

2) Acetaldehyde

Alcohol is broken down by your liver to something called Acetaldehyde, which is then further broken down to acetic acid.

Acetaldehyde is a toxic substance that breaks down to form “free-radicals” which wreak havoc on your insides.

During periods of over-indulgence, acetaldehyde levels start to rise because your liver can only process one drink per hour (depending on factors such as height, weight, and gender).

Your liver produces antioxidants that neutralize free radicals before they cause too much damage. You can also get antioxidants from the food you eat.

However, if you’re drinking more than your liver can process, this system is overrun as acetaldehyde levels start to build.

So now that we’ve got the science out the way, let’s look at how hangover pills work.

How do hangover pills work?

Hangover pills are designed to provide your liver with natural antioxidants to support your liver during periods of over-indulgence.

The best products are made from all-natural ingredients that work together to give your liver the best chance of coping with the toxic by-products of alcohol metabolism.

But before we go further…

It’s important to mention that there is no such thing as a magic ‘hangover cure’.

The hangover pills mentioned in this article are designed to support naturally support your body when drinking alcohol.

If you’re planning on getting wasted and wake up the next morning with no hangover, you’ll be disappointed.

What are the best hangover pill ingredients?

It’s worth knowing a bit more about the best ingredients to look for in a hangover pill so you can assess which product is the best value for money.

We’ve picked out some of the best ingredients to look for below:

Also known as DHM and Ampelopsin, this is one of the most popular hangover pill ingredients out there. Recent research has shown that it could increase the rate at which your liver breaks down alcohol.

Ginger is known for its ability to ease nausea symptoms and improve digestion. Therefore it’s always good to see this included in a hangover pill.

N-Acetyl Cysteine
It’s believed that this amino acid is used by the liver to produce Glutathione, which is known as your body’s “master antioxidant”

B Vitamins
B-vitamins are cofactors used by your liver to produce and regenerate the enzymes which break down alcohol.

Milk Thistle
You’ll find milk thistle in pretty much any liver health supplement for good reason. It’s known for its antioxidant and anti-inflammatory properties.

Prickly pear
Prickly pear is the fruit of a cactus plant that is high in polyphenols. Polyphenols are known to be powerful antioxidants.

Black pepper extract (Piperine)
We always like to see the inclusion of black pepper extract because it works as a bioavailability enhancer. This means that it increases the absorption of the other ingredients in your supplement and therefore ensures you get the most out of it.

Ingredients to avoid

Stimulants like caffeine can make you feel worse as they increase your heart rate and make you feel more on edge. In addition, caffeine is also a diuretic which can lead to further dehydration.

Proprietary blends
It’s hard to find supplements without a proprietary blend nowadays. If you take a closer look at the ingredients label in your supplement, you may see that several ingredients come under a mysterious “blend”.

The problem with them is that you aren’t able to see the exact doses of each ingredient in the blend. Depending on how the batch is made, you may get very small doses of key ingredients.

Proprietary blends are often used by manufacturers as they are much cheaper to produce and increase margins. Therefore, we always like to go for brands who don’t use them.

Artificial fillers /coloring
I think you’ll agree with the reason for not wanting artificial filler and coloring is self-explanatory.

Best 5 hangover pills

1) AfterDrink

Product website:

AfterDrink hangover pills


We found AfterDrink to be the best product we tried. It has a comprehensive list of all the ingredients required to combat the hangovers.


All of the ingredients are dosed properly and there are no proprietary blends.  It is all-natural, they use vegetarian capsules instead of gelatine ones many companies use – and they include no drugs or caffeine. It’s as pure as it gets when it comes to hangover pills.

Where do they sell?

AfterDrink sells all over the world. They manufacture their product in the UK and USA in GMP certified facilities. However, it’s not cheap. It’s a premium product and priced as such.

Side effects

All of AfterDrink’s ingredients are natural and safe to take. If you take any regular medications, you should still check with your doctor to make sure the herbal extracts don’t interact with them. Most of the hangover pills we review and recommend will have all-natural ingredients, so generally, the side-effect profile will be low.


The manufacturers advise taking three capsules before bed and three in the morning after drinking alcohol. The most important dose is before bed though, so make sure you don’t forget. This is generally the case with all hangover pills.

For more information and to buy now, visit

2) Flyby

Flyby hangover pill


Flyby is one of the new kids on the block. They’ve based their ingredients on a solid foundation and include everything you need in a hangover pill. The only issue: They use a proprietary blend.


Like most hangover pills, Flyby recommends taking three capsules before the start of your night and three at the end. It comes in two different sizes. The smaller bottle has 30 pills which means it’ll last you for five nights out and the bigger one has 90 pills, which will last you 15 nights out.

For more information and to buy Flyby now, visit Amazon

3) DeToxx

DeToxx hangover pill

DeToxx is like a “drink buffer”. You won’t magically feel amazing the day after taking PreToxx and having a big night out, but you will feel a lot less bad then if you didn’t take the hangover pills.


A veteran in the hangover supplement world. DeToxx used to be called PreToxx and contains most of the ingredients needed in a hangover pill. The reason it gets the third spot on the podium is because of its price. It’s a cheap and good value for money.


Because it’s cheap, they’ve sacrificed on a few key ingredients such as Turmeric and Ginger. They also use a proprietary blend, which means you don’t actually know how much of each ingredient you are getting.

For more information and to buy DeToxx now, visit Amazon

4) Cheers Hangover Pill

cheers hangover pill

Thrive pills actually lives up to a lot of the hype surrounding it.


Thrive hangover pills are pretty good. They have good doses of ingredients including almost 1 gram of DHM, which is a key ingredient in flushing out more alcohol from the system at the end of the night.


Most importantly, Thrive doesn’t use a proprietary blend, so you know exactly what you’re getting from each ingredient.


Thrive recommends taking three pills before bed only. This means that each bottle will last you a long time, as most other hangover pills recommend a total of six pills for each night out. But we aren’t too convinced that three pills are enough to really settle your hangover symptoms.

For more information and to buy Cheers now, visit Amazon

5) Drinkwel

Drinkwel for hangovers

Drinkwel claims to be just a multivitamin, and that’s all the product is –  an everyday Liver health multivitamin!

Drinkwel is one of the OGs in the hangover pill world. They have a lot of loyal customers who have stuck with them from day one.

They don’t get a higher spot on the podium for a few reasons:

1) They include too many ingredients – so each one is under-dosed. You can’t realistically fit in that many ingredients in a few tiny capsules.

2) They recommend taking two capsules a day and increasing the dose when drinking. So it’s a bit confusing whether they are more of a liver detox blend or a hangover pill.

3) Drinkwel uses a proprietary blend.

For more information and to buy Drinkwel now, visit Amazon

Anything else to consider?

When it comes to hangovers, prevention is always key. It’s always important to also make sure that you drink plenty of water during and after consuming alcohol.

In addition, having a meal before going out can go a long way in preventing the worst hangovers.

The hangover pills mentioned above are only designed to support your liver function.

The only thing you can do to guarantee that you don’t get a hangover is not to drink at all in the first place.

Conclusion – Our Final Thoughts

That brings us to the end of our look into the best available hangover pills.

AfterDrink is currently our top-rated product on the market right now.

From our experience, the IV solutions that have become popular in recent years do work – but frankly, they are too expensive to be anything more than a novelty at the moment.

‘Hangover patches’, meanwhile, aren’t quite as good as hangover pills or drinks as they can only deliver small amounts of the essential vitamins. Also, if you’ve got sensitive skin, you may end up with red and itchy patches, which isn’t a great addition to a hangover.

We will be constantly updating this list of supplements, and if you know of, or are a manufacturer your own hangover pills, then do get in touch with us and we’ll arrange to try them out and add them to the rankings above.

James Petra

James is a beer-loving Biochemist and natural health enthusiast from Hull, which is in Yorkshire, England.

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